Yes, the sentence is grammatically correct.
The sentence expresses a feeling of extreme discomfort and seeks advice or strategies for coping with that discomfort.
Here are a few possible rephrasings:
1. "Nothing feels as uncomfortable as this. How do you manage it, please?"
2. "I can't think of anything more uncomfortable than this. What do you do to cope, if you don't mind sharing?"
3. "This is the most uncomfortable situation I've


