what is the lethal does of Benadryl

The lethal dose of diphenhydramine, the active ingredient in Benadryl, can vary widely depending on the individual, including factors like age, weight, overall health, and specific medical conditions. While there isn't a universally accepted "lethal dose," significant toxicity can occur at doses much higher than the recommended therapeutic doses. For adults, the typical therapeutic dose for allergic reactions is 25-50 mg every 4-6 hours as needed, with a maximum of 300 mg per day. Some reports suggest that doses around 500 mg or higher could potentially be life-threatening, especially if taken in conjunction with other substances like alcohol or sedatives. In children, even smaller doses can be dangerous, and it's important to keep medications like Benadryl out of reach. If there is any concern about overdose or toxicity, it is crucial to seek immediate medical attention. Always use medications according to the guidance of a healthcare professional.